Structure of DNA (Deoxyribonucleic Acid)
- Double Helix
- DNA is shaped like a twisted ladder called a double helix.
- The two strands twist around each other.
- Backbone
- The sides of the “ladder” are made of sugar (deoxyribose) + phosphate groups.
- These form the sugar-phosphate backbone.
- Nitrogenous Bases
- The “rungs” of the ladder are paired nitrogenous bases:
- Adenine (A) ↔ Thymine (T)
- Guanine (G) ↔ Cytosine (C)
- Base pairs are held together by hydrogen bonds.
- A–T: 2 hydrogen bonds
- G–C: 3 hydrogen bonds
- The “rungs” of the ladder are paired nitrogenous bases:
- Antiparallel Strands
- The two DNA strands run in opposite directions (one 5′ → 3′, the other 3′ → 5′).
- Major and Minor Grooves
- Twisting creates grooves where proteins can bind for replication and transcription.
Functions of DNA Structure
- Stores genetic information in the sequence of bases.
- Allows replication because strands can separate and copy themselves.
- Facilitates transcription into RNA for protein synthesis.
In short:
DNA is a double-stranded helix made of a sugar-phosphate backbone and paired nitrogenous bases (A–T, G–C), which stores and transmits genetic information.