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What is the difference between sensitivity and specificity?

Sensitivity

  • Can the method detect very small amounts?
  • Example: Finding tiny traces of lead in water.
  • Remember: “Can I see it if it’s there?”

Specificity

  • Can the method measure only the substance I want?
  • Example: Measuring caffeine in coffee without being affected by sugar.
  • Remember: “Am I measuring the right thing?”

Simple rule:

  • Sensitive = Can detect small amounts
  • Specific = Can detect the correct substance

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