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What is spectrophotometry?

Spectrophotometry is a technique used in quantitative analysis to measure the amount of light absorbed or transmitted by a substance at a specific wavelength. It helps determine the concentration of a substance in a solution.

Key Points:

  1. Principle:
    • Based on Beer–Lambert Law, which states that the absorbance of light by a solution is directly proportional to the concentration of the absorbing substance and the path length of the light.
    • Absorbance (A) = ε × c × l, where:
      • ε = molar absorptivity
      • c = concentration
      • l = path length of the light through the solution
  2. How it Works:
    • A beam of light of a specific wavelength passes through the solution.
    • A detector measures the intensity of light before and after passing through the solution.
    • The decrease in light intensity (absorbance) is used to calculate the concentration.
  3. Uses:
    • Measuring concentration of colored solutions (e.g., iron, copper ions).
    • Enzyme activity assays in biochemistry.
    • Monitoring chemical reactions.
  4. Advantages:
    • Highly sensitive and accurate.
    • Requires very small amounts of sample.
    • Quick and non-destructive.

In short: Spectrophotometry is a method to measure how much light a substance absorbs, which allows scientists to determine its concentration in a solution.

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