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What is the structure of DNA?

Structure of DNA (Deoxyribonucleic Acid)

  1. Double Helix
    • DNA is shaped like a twisted ladder called a double helix.
    • The two strands twist around each other.
  2. Backbone
    • The sides of the “ladder” are made of sugar (deoxyribose) + phosphate groups.
    • These form the sugar-phosphate backbone.
  3. Nitrogenous Bases
    • The “rungs” of the ladder are paired nitrogenous bases:
      • Adenine (A) ↔ Thymine (T)
      • Guanine (G) ↔ Cytosine (C)
    • Base pairs are held together by hydrogen bonds.
      • A–T: 2 hydrogen bonds
      • G–C: 3 hydrogen bonds
  4. Antiparallel Strands
    • The two DNA strands run in opposite directions (one 5′ → 3′, the other 3′ → 5′).
  5. Major and Minor Grooves
    • Twisting creates grooves where proteins can bind for replication and transcription.

Functions of DNA Structure

  • Stores genetic information in the sequence of bases.
  • Allows replication because strands can separate and copy themselves.
  • Facilitates transcription into RNA for protein synthesis.

In short:

DNA is a double-stranded helix made of a sugar-phosphate backbone and paired nitrogenous bases (A–T, G–C), which stores and transmits genetic information.


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