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What are isomers?

Isomers are compounds that have the same molecular formula (same number and types of atoms) but different arrangements of atoms, resulting in different properties.

Types of Isomers

  1. Structural (Constitutional) Isomers
    • Atoms are connected in different ways.
    • Types:
      • Chain isomers – different arrangements of the carbon chain.
      • Position isomers – functional group or substituent at different positions.
      • Functional group isomers – same formula but different functional groups (e.g., alcohol vs ether).
  2. Stereoisomers
    • Atoms are connected the same way but arranged differently in 3D space.
    • Types:
      • Geometrical isomers (cis/trans or E/Z) – due to restricted rotation around double bonds or rings.
      • Optical isomers (enantiomers and diastereomers) – differ in chirality and mirror-image relationships.

Importance of Isomers

  • They often have very different physical and chemical properties despite having the same formula.
  • In biology and medicine, different isomers can have completely different effects (e.g., one isomer of a drug may be therapeutic, while another may be harmful).

In short: Isomers are like different “arrangements” of the same building blocks, giving rise to distinct compounds.

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