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What is the role of molecular orbitals in chemical reactivity?

Here’s a explanation of the role of molecular orbitals (MOs) in chemical reactivity:


1. Molecular Orbitals and Electrons

  • Molecular orbitals are regions where electrons are most likely to be found in a molecule.
  • Electrons in these orbitals determine how a molecule can interact with others.

2. HOMO and LUMO

Two orbitals are especially important for reactivity:

  1. HOMO (Highest Occupied Molecular Orbital)
    • Contains the most reactive electrons in a molecule.
    • Acts as an electron donor in reactions.
  2. LUMO (Lowest Unoccupied Molecular Orbital)
    • The lowest energy orbital that is empty.
    • Can accept electrons from another molecule.

Key idea:

  • Chemical reactions often occur when electrons move from the HOMO of one molecule to the LUMO of another.

3. Predicting Reactivity

  • MO theory helps explain:
    • Why some molecules are more reactive than others.
    • The sites in a molecule where reactions are likely to happen.
    • Stability of molecules (delocalized MOs → more stable).

Example:

  • In ethene (C₂H₄), the π bond electrons (in HOMO) can react with electrophiles (species that accept electrons) because the π electrons are easily accessible.

4. Summary

  • MOs show where electrons are.
  • HOMO → donor, LUMO → acceptor.
  • Reactivity is controlled by how electrons in MOs interact with other molecules.

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