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What is the difference between nucleophilic and electrophilic substitution?

Nucleophilic Substitution

  • Who attacks: Nucleophile (electron-rich).
  • Where it attacks: Carbon with a leaving group (electron-poor).
  • Example: OH⁻ replaces Cl in CH₃Cl → CH₃OH.
  • Think: “Nucleophile loves positive carbon.”

Electrophilic Substitution

  • Who attacks: Electrophile (electron-poor).
  • Where it attacks: Electron-rich part of a molecule (often benzene).
  • Example: NO₂⁺ replaces H on benzene → nitrobenzene.
  • Think: “Electrophile loves electron-rich area.”

Easy trick:

  • Nuc → attacks carbon
  • Electro → attacks electrons (aromatic rings)

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