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What is split and splitless injection in GC?

Here’s a explanation of split and splitless injection in GC:


1. Split Injection

  • Only a small part of the sample goes into the column.
  • The rest is vented out.
  • Used for: Samples with high concentration.
  • Pros: Sharp peaks, column doesn’t get overloaded.
  • Cons: Not good for very tiny amounts.

2. Splitless Injection

  • Almost all of the sample goes into the column.
  • The split vent is closed during injection.
  • Used for: Trace or very dilute samples.
  • Pros: Very sensitive.
  • Cons: Column can overload if sample is too strong.

In short:

  • Split → small amount in → high concentration.
  • Splitless → all sample in → low concentration.

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