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How is chromatography used in drug testing?

Chromatography is very important in drug testing because it can detect, separate, and identify drugs or their metabolites in small samples like blood, urine, or hair. Here’s a explanation:


1. Detecting Illegal Drugs

  • Chromatography can find substances like cocaine, heroin, marijuana, or amphetamines in the body.
  • Even tiny amounts can be detected because chromatography is very sensitive.

2. Separating Compounds

  • Blood or urine contains many substances.
  • Chromatography separates the drug from all other compounds, making it easier to identify.

3. Identifying Specific Drugs

  • After separation, techniques like mass spectrometry or UV detection can confirm exactly which drug is present.
  • This helps in legal cases or workplace testing.

4. Measuring Drug Levels

  • Chromatography can also measure how much of the drug is in the sample.
  • This helps determine recent usage, dose, or exposure.

5. Testing Performance-Enhancing Drugs

  • Used in sports doping tests to detect substances like steroids or stimulants in athletes’ blood or urine.

6. Monitoring Prescribed Medications

  • Doctors or labs can use chromatography to check if a patient is taking the right amount of medication.

In Short:

Chromatography is used in drug testing to:

  • Detect illegal or prescription drugs
  • Separate them from other substances
  • Identify exactly which drug is present
  • Measure the amount in the body

It is widely used in forensic labs, hospitals, sports testing, and workplace drug screening because it is accurate and reliable.


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