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How are enzymes classified in biochemistry?

Enzymes are divided into six main classes based on the type of reaction they help in.
Here is a simple explanation:


1. Oxidoreductases

  • Help in oxidation and reduction (redox) reactions.
  • They transfer hydrogen or electrons from one molecule to another.
  • Example: Dehydrogenase, Oxidase.

2. Transferases

  • Transfer a chemical group (like a phosphate or amino group) from one molecule to another.
  • Example: Kinase, Transaminase.

3. Hydrolases

  • Break large molecules into smaller ones by adding water (hydrolysis).
  • Important in digestion.
  • Example: Amylase, Protease, Lipase.

4. Lyases

  • Break or form bonds without using water.
  • They may form double bonds or remove groups from molecules.
  • Example: Decarboxylase, Aldolase.

5. Isomerases

  • Rearrange the structure of a molecule to form an isomer.
  • Example: Isomerase, Mutase.

6. Ligases (or Synthetases)

  • Join two molecules together using energy from ATP.
  • Example: DNA ligase, Aminoacyl-tRNA synthetase.

In short:

  • Oxidoreductases – oxidation or reduction
  • Transferases – transfer groups
  • Hydrolases – break with water
  • Lyases – break without water
  • Isomerases – rearrange atoms
  • Ligases – join molecules

These six classes cover all enzyme-catalyzed reactions in living cells.

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